COVID Without Symptoms May Be Very Rare

Newest Coronavirus Information

COVID Without Symptoms May Be Very Rare

THURSDAY, Feb. 17, 2022

Wholesome, unvaccinated adults who get COVID are unlikely to be symptom-free, in keeping with a brand new research that challenges different analysis suggesting that asymptomatic an infection is widespread.

“Some research recommend that asymptomatic an infection could happen as typically as 50% of the time,” however the brand new analysis casts doubt on that assertion, stated senior creator Dr. Edward Mitre. He is a professor of microbiology and immunology at Uniformed Companies College of the Well being Sciences (USUHS) in Bethesda, Md.

The new study included 263 uninfected, unvaccinated well being care staff (common age: 41) on the Walter Reed Nationwide Army Medical Middle in Bethesda. They had been usually wholesome and had regular immune techniques.

Between August 2020 and February 2021, the contributors took PCR exams every time they’d signs. In addition they underwent month-to-month antibody testing to detect any circumstances of COVID that had been symptom-free or missed by PCR testing.

The contributors had been additionally requested to self-report any signs.

In all, 12 contributors examined constructive for SARS-CoV-2 an infection and all had signs, in keeping with findings revealed Feb. 14 in Open Forum Infectious Diseases.

If asymptomatic infection happens as typically as 50% of the time as earlier research have prompt, Mitre stated, it could have been “not possible” to have seen signs in all 12 of those that had been contaminated on this research.

“If we evaluate this to flipping a coin, the chance that one flips tails 12 occasions in a row is barely 0.024%,” he stated in a college information launch. “Even when the true fee of asymptomatic an infection is 30%, then the chance that 12 of 12 people would all be symptomatic remains to be only one.4%.”

Mitre famous that this research was performed on an unvaccinated inhabitants and should not mirror charges of asymptomatic an infection in vaccinated people.

Lead creator Emilie Goguet, additionally from USUHS, stated researchers suspect they noticed a better fee of symptomatic an infection as a result of research contributors had been paying shut consideration to indicators of an infection.

She stated the research’s design most likely additionally helped. All through the autumn and winter, contributors reported signs any day they skilled a departure from their baseline well being.

As a part of the research, the researchers additionally in contrast signs within the 12 individuals who had been identified with COVID to these in 38 contributors who developed non-COVID-19 respiratory sicknesses.

Runny nose, sinus strain and sore throat occurred in additional than 70% of each teams. Each additionally had comparable charges of loss of smell or style.

These findings present that it isn’t doable to reliably differentiate COVID from different respiratory tract infections primarily based on signs alone, in keeping with the researchers.

Extra data

For extra on COVID-19 signs, see the U.S. Centers for Disease Control and Prevention.

SOURCE: Uniformed Companies College of the Well being Sciences, information launch, Feb. 14, 2022

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