Allergic Reaction to Your First COVID Shot? Risk of Another Is Low

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Allergic Reaction to Your First COVID Shot? Risk of Another Is Low

WEDNESDAY, Feb. 23, 2022

So, you had a severe allergic reaction to your first COVID-19 shot. Does that doom you to the identical after your second shot?

Apparently not, claims a brand new evaluation that discovered the chance of a second vaccine dose response is extraordinarily low.

Proper now, the advice for somebody who has had a extreme response to the primary dose of a COVID-19 vaccine is to not get one other. However amongst greater than 1,300 sufferers who had a extreme allergic reaction to a primary jab, almost 100% tolerated a second shot, the researchers discovered.

By a extreme allergic response, researchers imply swelling and shutting of the airway, known as anaphylaxis, which makes it onerous to breathe and might be deadly.

“Individuals who’ve had a direct allergic reaction to the primary dose of an mRNA COVID-19 vaccine might be safely revaccinated and obtain a second dose below allergist supervision, permitting individuals to have the ability to obtain a full vaccination sequence,” stated lead researcher Dr. Matthew Greenhawt. He’s a professor of pediatrics on the College of Colorado Faculty of Medication, in Aurora.

“This has the potential to vary present follow and additional forestall COVID-19 transmission and extreme COVID-19 outcomes,” he added.

For the examine, Greenhawt’s workforce analyzed 22 beforehand revealed research, which included greater than 1,300 adults who had a direct allergic response to their first dose of the COVID-19 vaccine.

Pooling their knowledge, a course of referred to as meta-analysis, the researchers discovered that six sufferers had a direct allergic response after their second shot. Almost 14% had a light allergic response, however greater than 99% tolerated the second shot.

Amongst 78 individuals who had a extreme quick allergic response to their first vaccination, 4 had a extreme quick response to their second shot and 15 had gentle signs, and nobody died from their allergic response, the researchers reported.

The findings had been revealed on-line Feb. 21 in JAMA Internal Medicine.

Dr. Matthew Harris is medical director of Northwell Well being’s COVID-19 Vaccination Program in New Hyde Park, N.Y. He stated, “It is reassuring that there have been a whole bunch of tens of millions of doses given around the globe, and absolutely the danger for anaphylaxis is remarkably uncommon, and I feel it reinforces the security profile of those essential vaccines.”

Harris famous that when the vaccines had been new, individuals who had even gentle reactions, like hives, had been referred to an allergist. However these findings present that it is secure to get a second shot and even a booster.

“I feel the examine is fairly clear that it’s overwhelmingly secure to go forward and get that booster,” he stated.

If sufferers are reluctant to get a second shot or a booster, Harris suggests having a dialogue with their physician or an allergist.

He additionally identified that individuals with allergies are sometimes these at excessive danger for a extreme bout of COVID-19 and might actually profit from being absolutely vaccinated.

Harris added {that a} life-threatening response to a COVID-19 vaccine could be very uncommon.

“At Northwell, I evaluation each single opposed medical occasion from the vaccine, and we have vaccinated 700,000 neighborhood members and one other 65,000 workforce members, and I can let you know that within the final 9 months, I do not recall a single episode of anaphylaxis,” he stated.

Extra info

For extra on COVID-19 vaccinations, head to the U.S. Centers for Disease Control and Prevention.

SOURCES: Matthew Greenhawt, MD, professor, pediatrics, College of Colorado Faculty of Medication, Aurora; Matthew Harris, MD, medical director, Northwell Well being COVID-19 Vaccination Program, New Hyde Park, N.Y.; JAMA Inside Medication, Feb, 21, 2022, on-line

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